{"product_id":"g6pdh","title":"G6PDH","description":"\u003cp\u003e\u003cspan\u003eGlucose-6-phosphate dehydrogenase (G6PD) deficiency is a hereditary disorder caused by a defect in the G6PD enzyme, crucial for protecting red blood cells from oxidative damage. This enzyme is essential in the pentose phosphate pathway, where it helps produce NADPH, needed to maintain reduced glutathione, a key antioxidant. Without sufficient NADPH, red blood cells become vulnerable to oxidative stress, leading to hemolysis. The condition is X-linked, primarily affecting males. Females with two defective gene copies (homozygous or compound heterozygous) can also show symptoms, while most heterozygous females are asymptomatic carriers. Triggers like fava beans, aspirin, or sulfonamides can cause acute hemolytic anemia, presenting as jaundice, fatigue, shortness of breath, or in severe cases, shock. The G6PDH test uses glucose-6-phosphate substrate colorimetric method with nitrotetrazolium blue chloride (NBT) to detect enzyme activity through visual color formation. Measuring G6PD enzyme activity is crucial for diagnosis and management, enabling healthcare providers to identify at-risk patients and prevent hemolytic episodes.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eCheck \u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0973\/1827\/3323\/files\/ENCORE_-_G6PD_-_VER_01.pdf?v=1767334670\" rel=\"noopener\" style=\"color: rgb(255, 42, 0);\" target=\"_blank\"\u003eHERE \u003c\/a\u003e\u003c\/span\u003eInstructions For Use (Pack Insert)\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Enssure","offers":[{"title":"10 TESTS \/ Exp.: APR. 2027","offer_id":51679591596331,"sku":null,"price":800.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0973\/1827\/3323\/files\/G6-05.jpg?v=1766730892","url":"https:\/\/shop.encorebiomedicals.com\/products\/g6pdh","provider":"Encore Biomedicals ","version":"1.0","type":"link"}