{"product_id":"sickle-cell-solubility-test","title":"SICKLE CELL SOLUBILITY","description":"\u003cp\u003e\u003cspan\u003eHemoglobin S (Hb S) differs from normal Hemoglobin A (Hb A) by a single amino acid change—valine replaces glutamic acid at position 6 of the beta chain. This causes red blood cells to become sickle-shaped under low oxygen conditions, leading to blood vessel blockages and anemia. Individuals with sickle cell anemia (S\/S) face severe symptoms and early mortality, while those with the trait (NS) are usually asymptomatic but may experience crises under low oxygen conditions. The Sickle Cell Solubility Test is based on the solubility difference between Hb S and Hb A in concentrated phosphate buffer solution. This reliable screening method enables healthcare providers to quickly identify the presence of hemoglobin S, facilitating early diagnosis and appropriate patient management. The test utilizes sodium dithionite in concentrated phosphate buffer to cause Hb S precipitation while keeping Hb A soluble, providing clear visual differentiation between normal and abnormal hemoglobin variants.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eCheck \u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0973\/1827\/3323\/files\/ENCORE_-_SICKLE_SOLUBILITY.pdf?v=1767335315\" rel=\"noopener\" style=\"color: rgb(255, 42, 0);\" target=\"_blank\"\u003eHERE \u003c\/a\u003e\u003c\/span\u003eInstructions For Use (Pack Insert)\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"product-form__input product-form__quantity product-form__quantity-top\" id=\"Quantity-Form-template--26031733440811__main\"\u003e\u003c\/div\u003e","brand":"Enssure","offers":[{"title":"50 TESTS \/ Exp.: JAN 2028 \/ Exp.: FEB. 2028","offer_id":51679740166443,"sku":null,"price":750.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0973\/1827\/3323\/files\/SICKELCELLSOLUBITI-01.jpg?v=1773118777","url":"https:\/\/shop.encorebiomedicals.com\/products\/sickle-cell-solubility-test","provider":"Encore Biomedicals ","version":"1.0","type":"link"}