{"product_id":"soluble-fms-like-tyrosine-kinase-1","title":"Soluble Fms-like Tyrosine kinase-1","description":"\u003cp\u003e\u003cspan\u003eThis assay is intended for the in vitro quantitative determination of soluble fms-like tyrosine kinase-1 (sFlt-1) in human serum and plasma. Used together with the PlGF assay, it helps determine the sFlt-1\/PlGF ratio, which assists in diagnosing preeclampsia alongside other clinical information. sFlt-1 is a multi-glycosylated protein of about 100 kDa, acting as an anti-angiogenic factor by binding vascular endothelial growth factor (VEGF) and preventing its interaction with cell surface receptors, thereby inhibiting VEGF's biological activity. Preeclampsia, affecting 2-8% of pregnancies globally, is characterized by hypertension and organ dysfunction after 20 weeks of pregnancy. In preeclampsia, sFlt-1 levels increase significantly while PlGF levels decrease compared to normal pregnancies, disrupting placental vascular development. Measuring the sFlt-1\/PlGF ratio provides valuable diagnostic insight into preeclampsia risk and progression. Common testing methods include ELISA, chemiluminescence, and immunofluorescence.\u003c\/span\u003e\u003c\/p\u003e","brand":"Enlight","offers":[{"title":"12 TESTS","offer_id":52728824791339,"sku":null,"price":0.0,"currency_code":"INR","in_stock":false},{"title":"24 TESTS","offer_id":52728824824107,"sku":null,"price":0.0,"currency_code":"INR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0973\/1827\/3323\/files\/SFLT-01.jpg?v=1772788039","url":"https:\/\/shop.encorebiomedicals.com\/products\/soluble-fms-like-tyrosine-kinase-1","provider":"Encore Biomedicals ","version":"1.0","type":"link"}