This assay is used for the quantitative determination of C-Reactive Protein (CRP) in human serum, plasma, and whole blood. CRP is a highly sensitive acute-phase protein produced by the liver in response to inflammation, consisting of five identical subunits forming a ring structure. In healthy individuals, CRP levels are typically below 8 mg/L, but during acute inflammation, levels rise rapidly within 6–12 hours and peak within 24–48 hours. Values above 100 mg/L often indicate severe infections or trauma, while the response may be reduced in liver disease. CRP testing helps detect inflammation, monitor infections and treatment response, identify complications after surgery, and differentiate between active and inactive disease states. Persistently high CRP levels usually suggest an ongoing, uncontrolled infection and may indicate a poor prognosis.
